WebbRibonucleoproteins (RNPs) comprise one or more RNA and protein molecules that interact to form a stable complex, which commonly involves conformational changes in the more flexible RNA components. Here, we propose that Cas12a RNP assembly with its cognate CRISPR RNA (crRNA) guide instead proceeds primarily through Cas12a conformational … Webbför 2 dagar sedan · Next, the GoF test suggests that the average p-value across our 1000 simulated time-series is 30.08%.Moreover, in 671 out of 1000 simulated series, we cannot reject the power-law null hypothesis because the p-values exceed 0.05. 11 The maximum time length of the processes being in power-law regimes is, on average, 9.81 time units, …
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