Phosphopantetheine attachment site
WebPhosphopantetheine (or pantetheine 4' phosphate) is the prosthetic group of acyl carrier proteins (ACP) in some multienzyme complexes where it serves as a 'swinging arm' for … WebSep 2, 2014 · There is a phosphopantetheine attachment site spanning residues G 143 to M 164 in AhDGAT1-1 (G 157 to M 178 in AhDGAT1-2). A putative thiolase acyl-enzyme intermediate binding motif, previously cited in the Arabidopsis sequence by Zou et al. (1999) , is also found in AhDGAT1. It contains an invariant Pro208 at the N-terminus of this motif …
Phosphopantetheine attachment site
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WebSep 29, 2024 · Phosphopantetheine attachment site. A 4'-phosphopantetheine prosthetic group is attached through a serine. This prosthetic group acts as a a 'swinging arm' for the … WebJan 10, 2024 · To obtain active CAR enzyme, a phosphopantetheine group must be attached covalently to a conserved serine in the PCP domain mediated by a suitable …
WebAug 16, 2024 · Most chemical modifications made to proteins within cells occur after the protein is synthesized in a process called translation. The resulting chemical changes are … Webthis effect was dependent upon an intact phosphopantetheine attachment site (PPAS) motif within the α/β hydrolase fold of NDRG1. Materials and Methods. Cell lines and culture. BeWo, JEG-3, CHO, and NIH3T3 lines were purchased from ATCC (Manassas, VA) and cultured as we previously detailed [38-41]. We also previously characterized and detailed the
WebJan 6, 2024 · The Psc_Aza_B gene is predicted to encode a non-reducing polyketide synthase composed of ve modules: ACP transacylase, β-ketoacyl synthase, acyltransferase phosphopantetheine attachment site and ... WebDownload scientific diagram Phylogenetic analysis of CARs. A) Domain organization of CAR sequences: adenylation domain (PFam PF00501), phosphopantetheine (PP) …
Weband acyl carrier protein [also known as a phosphopantetheine attachment site (PP) domains]. The KS, AT, and PP domains are essential for both FASs and PKSs, whereas the KR, DH, and ER domains are present in all FASs, but some or all are absent in various PKSs. KR, DH, and ER domains catalyze, in a stepwise
WebMar 21, 2024 · This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ( [ACP]) domain. ( FAS_HUMAN,P49327 ) (Microbial infection) Fatty acid synthetase activity is required for SARS coronavirus-2/SARS-CoV-2 replication. ( FAS_HUMAN,P49327 ) did flamingo win a bloxyWebAug 1, 2015 · Phosphopantetheine attachment site: Dieckmanna Cyclase (DKC) NADB-Rossmann: I3810-R4092: NAD(P)-binding motif: ORF3 (fumoA) encodes a cytochrome P450 monooxygenase which maybe catalyzes an unprecedented oxidative ring expansion of prefumosorinone A to form the 2-pyridone core of fumosorinone (Halo et al., 2008a). … did flamingo albert quit kiss a guyWeb4'-Phosphopantetheine C11H23N2O7PS CID 115254 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological ... did five nights at freddy\\u0027s really happenWebDefinition: Interacting selectively and non-covalently with the attachment site of the phosphopantetheine prosthetic group of an acyl carrier protein (ACP) as part of the process of fatty acid biosynthesis. ID: GO:0000036 Synonyms: Articles referencing this term. Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork ... did fixer upper castle sellhttp://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00823 did five kids go missing at chuck e cheeseWebphosphopantetheine (or pantetheine 4' phosphate) (Ppant) prosthetic group that is covalently attached to an invariant serine residue of the CP domain. CP domains, typically … did flagstar buy wells fargoWebSep 1, 2000 · Motifs I and III have been associated with ATP-binding and hydrolysis activities, respectively, since motif X contains a conserved serine to which a 4′-phosphopantetheine cofactor is very probably attached [ 3 ]. did five finger death punch serve in the army