WebApr 13, 2024 · HCT116, HCT116 p53 −/−, and HCT116-5FUR cells were treated with mannose (50 mM) and 5-FU (5 μM) alone or in combination for up to 72 h. Cells treated … WebCollateral sensitivity of the resistant HCT116 p53− /− colon adenocarcinoma cells to SCHL was observed as well as the normal sensitivity of CEM/ADR5000 leukemia cells, MDA-MB-231-BCRP breast adenocarcinoma cells and U87. MGΔEGFR glioblastoma cells. SCHL induced apoptosis in CCRF-CEM cells via caspases 3/7-, 8- and 9-activation, MMP ...
Consequences of DHX9 knockdown on p53 targets in HCT116 p53 …
WebMar 1, 2024 · We also developed an in-house reference p53 target gene data set by RNA-Seq and p53-dependent protein data set by proteomic analysis, using HCT116 and HCT116 p53 −/− cell lines treated with the known p53 activator 5-Fluorouracil (5-FU) as a positive control. p53 is inactivated in almost all human cancers, either by mutation, deletion, … nys sales tax warrant search
Influence of PHA680632 on cell cycle in p53wt vs p53−/− HCT116 …
WebJul 26, 2013 · HCT116 cells were treated with 26 μM ALLN for 24 h; significant cell death was detected in the HCT116 cells and HCT116/p53 −/− cells, but was inhibited in HCT116/Bax −/− cells (Fig. 3 B). Decreased pro-caspase-3 and cleaved PARP were seen in ALLN-treated HCT116 cells and HCT116/ p53 −/− cells, but pro-caspase-3 remained … WebThe interaction of two synthetic ω-conopeptides SNX111 (MVIIA) and SNX-230 (MVIIC) both derived from the marine snail Conus magus, with non-L-type neuronal voltage-sensitive calcium channels (VSCC) in rat brain synaptosomal preparations has been investigated with the aid of well-characterized 125 I derivatives of the two peptides. To assess the effects … WebDec 30, 2010 · ( A) HCT 116 (p53 +/+) cells were treated with increasing amounts of Adr (0.1, 0.5, 1 μM). Proteins were extracted for co-IP with anti-SIRT1 and probed with anti–pan-methyl-lysine ( Upper ). Methylation bands were scanned, and the relative band intensities were normalized to each SIRT1 band. magic the gathering cards walmart